CARDIAC LAB VALUES

Creatine Kinase aka Creatine Phosphokinase
CK-MB CK isoenzyme
(LDH) Lactate dehydrogenase
SGOT
Myoglobin
Troponin Complex

Creatine Kinase aka Creatine Phosphokinase (CK) - Levels rise 4 to 8 hours after an acute MI (Myocardial Infarction), peaking at 16 to 30 hours and returning to baseline within 4 days.

Creatine Kinase (male) 25 - 90 U/L
Creatine Kinase (female) 10 - 70 U/L

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CK-MB CK isoenzyme - It begins to increase 6 to 10 hours after an acute MI, peaks in 24 hours, and remains elevated for up to 72 hours.

Creatine Kinase-MB 0 - 5 U/L

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(LDH) Lactate dehydrogenase - Total LDH will begin to rise 2 to 5 days after an MI; the elevation can last 10 days.

LDH, serum: 45 - 90 U/L

LDH-1 and LDH-2 LDH isoenzymes - Compare LDH 1 and LDH 2 levels. Normally, the LDH-1 value will be less than the LDH-2. In the acute MI, however, the LDH 2 remains constant, while LDH 1 rises. When the LDH 1 is higher than LDH 2, the LDH is said to be flipped, which is highly suggestive of an MI. A flipped pattern appears 12-24 hours post MI and persists for 48 hours.

LDH-1: 18 - 33 percent
LDH-2: 28 - 40 percent

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SGOT - Serum glutamic oxaloacetic transaminase is an enzyme that is normally present in liver and heart cells. SGOT is released into blood when the liver or heart is damaged. The blood SGOT levels are elevated with liver damage (hepatitis) or with an insult to the heart (heart attack). There are some medications that can also raise SGOT levels. SGOT is also called aspartate aminotransferase (AST). SGOT will begin to rise in 8-12 hours and peak in 18-30 hours

10-42 U/L

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Myoglobin - early and sensitive diagnosis of myocardial infarction in the emergency department This small heme protein becomes abnormal within 1 to 2 hours of necrosis, peaks in 4-8 hours, and drops to normal in about 12 hours.

Myoglobin, serum (male): 10 - 95 ng/mL
Myoglobin, serum (female): 10 - 65 ng/mL

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Troponin Complex - Peaks in 10-24 hours, begins to fall off after 1-2 weeks.

Tropinin I: < 0.1 ng/mL
Tropinin T: < 0.1 ng/mL

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